Streptococcus pyogenes strains associated with invasive and non-invasive infections present possible links with emm types and superantigens

Objective(s): Streptococcus pyogenes, a notorious human pathogen is responsible to cause a wide range of infections varies from AAV9-cBIN1 gene therapy rescues chronic heart failure due to ischemic cardiomyopathy in a canine model superficial common clinical illness to severe and life threatening infections.To our knowledge this is the first report

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Gene Expression Profiling of NFATc1-Knockdown in RAW 264.7 Cells: An Alternative Pathway for Macrophage Differentiation

NFATc1, which is ubiquitous in many Environmental charges levied on power plants cell types, is the master regulator of osteoclastogenesis.However, the molecular mechanisms by which NFATc1 drives its transcriptional program to produce osteoclasts from macrophages (M) remains poorly understood.We performed quantitative PCR (QPCR) arrays and bioinfor

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